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Redefining the extension of Healthspan at the Cellular Level

At Mogling Bio, we are pioneering pharmacological solutions to restore the function of aged and exhausted cells—particularly stem cells—addressing a root cause of tissue degeneration and age-related diseases.
Our platform targets cellular aging to unlock new pathways for regenerative health, with the ultimate goal of compressing morbidity and extending Healthspan.
We are advancing a new class of therapeutics positioned at the intersection of aging biology and regenerative medicine—backed by science, driven by impact.

Science

Targeting Cdc42 to reverse Cellular Aging at its Core

At Mogling Bio, we are targeting a key driver for aging: Cdc42. This small but powerful protein becomes hyperactive as we age, disrupting cellular architecture and triggering functional decline. We are developing innovative therapies to specifically reduce the age-associated overactivation of Cdc42. By dialing down Cdc42 activity, we restore order inside aging cells to rejuvenate (stem) cell function to engineering rejuvenation.

This breakthrough approach unlocks the potential to combat a wide range of age-related diseases, from osteoporosis and immune dysfunction to blood disorders and neurodegeneration.

Team

Jürgen Reeß

EXTENSIVE EXECUTIVE EXPERIENCE
CO-FOUNDER

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Yi Zheng

CDC42/CASIN EXPERT
CO-FOUNDER

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Hartmut Geiger

STEM CELL AGING AND REJUVENATION EXPERT
CO-FOUNDER

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Anne Eldrup

MASTER OF SCIENCE, PHD

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Norbert Hauel

MEDCHEM EXPERT
INVENTOR OF TWO MOLECULES THAT BECAME BLOCKBUSTERS

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Board of Directors

Georg van Husen

EXPERIENCED PHARMA LEADER
CEO OF TENACIO

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Jürgen Reeß

EXTENSIVE EXECUTIVE EXPERIENCE
CO-FOUNDER

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Scientific advisory board members

Jan S. Rosenbaum

EXECUTIVE EXPERT
KUROME THERAPEUTICS, CINCINNATI

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Jose Cancelas-Perez

CELL THERAPY EXPERT
HOXWORTH BLOOD CENTER AND CINCINNATI CHILDREN‘S
HOSPITAL MEDICAL CENTER, CINCINNATI

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Carolina Florian

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Graham Pawelec

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News / Press

Video: Rejuvenation Startup Summit 2024 (YouTube)

Juergen Reess, Co-founder and CEO of MoglingBio presenting at the Rejuvenation Startup Summit 2024

Video: Rejuvenation of Old Stem Cells (YouTube)

Hartmut Geiger talks about his research on aging and stem cells and the influence of Casin on the biology.

fightaging.org reports about Mogling Bio

CASIN Alters Epigenetic State to Produce Lasting Improvement in Aged Stem Cell Function

Mogling Bio signs exclusive CASIN Licensing agreement

Mogling Bio entering Licensing Agreement with Cincinnati Children’s Hospital Medical Center

Kizoo invests in Rejuvenation Startup MoglingBio

Mogling Bio closes Seed Investment Round with Kizoo Technology Capital

Mogling Bio in Berlin, October 2022

Mogling Bio at the Rejuvenation Start-Up Summit in Berlin, October 14-15

Partnering

If you’re interested in exploring partnering or investment opportunities with Mogling Bio, please contact:
Mogling Bio Business Development
info@moglingbio.com

 

Interested In Meeting?

Find Us Here:

LSX World congress, Boston USA , Sep 11-12 2024

Longevity Investors Conference, Gstaad, Switzerland Sep 24-27 2024

Bio Europe, Stockholm, Nov 4-6 2024